CIMAR Lecture: Developing narrow spectrum antibiotics for Lyme Dr. Peter Gwynne talks about his use of metabolic mapping to identify unique vulnerabilities of Lyme disease and how he intends to repurpose common drugs into narrow spectrum antbioitics SearchSearchHome…

Hitchin’ a Ride: Exploiting the Tick-Bacteria Interface James Phelan is a scientist at the Tufts Lyme Disease Initiative working to find ways of reducing the numbers of Lyme-carrying mice and ticks. To do so, he is using next generation sequencing techniques to…

How Lyme Hides: Subverting the immune system for survival People catch Lyme disease from ticks, who in turn get the bacteria from wild mice. But why don’t mice get the same disease? We think it’s something to do with differences in the immune systems of mice and…

Feed Me: Hijacking the Lyme bacteria’s nutritional requirements Borrelia burgdorferi has a very small genome.  It is about ¼ the size of the genome for Escherichia coli (a common bacteria) or the tuberculosis bacteria or less than 1/1000 the size of the human genome. …